When and how to diagnose patent foramen ovale.

نویسنده

  • F J Pinto
چکیده

P atent foramen ovale (PFO) is a common finding in the healthy population, with a prevalence of 27% in one necropsy study of 965 normal hearts from patients with no history of cardioembolic events. It is also the most common cardiac finding in young patients (, 55 years of age) with an unexplained cerebrovascular event, presumably caused by paradoxical emboli. The presumed mechanism is the migration of a thrombus (or less commonly air or fat) from the venous system to the left atrium via a PFO, with subsequent systemic embolisation. Determining whether paradoxical embolism has occurred through a PFO ideally requires the presence of the PFO ‘‘triad’’, which combines raised right atrial pressure, venous source of thrombosis, and the presence of PFO. The larger size of a PFO and greater number of microbubbles passing through a shunt during echocardiography has also been associated with an increased incidence of cerebrovascular events 4

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عنوان ژورنال:
  • Heart

دوره 91 4  شماره 

صفحات  -

تاریخ انتشار 2005